You can wear many 5 mukhi rudraksha beads along with few 7 mukhi rudraksha for Saturn and Jupiter combined issues. Ganesha rudraksha also helps a lot in neutralizing the despair that comes out from such situations.
It will be better if u ask for the astrological recommendation by giving your birth details. Please apply for free rudraksha recommendation. Please go through the link and put in all your details and submit the form. After our astrologer sees the details, he will send the rudraksha recommendation based on your jatakam/Kundali.